The House Of Medici: Its Rise and Fall- It was a dynasty with more wealth, passion, and power than the houses of Windsor, Kennedy, and Rockefeller combined. It shaped all of Europe and controlled politics, scientists, artists, and even popes, for three hundred years. It was the house of Medici, patrons of Botticelli, Michelangelo and Galileo, benefactors who turned Florence into a global power center, and then lost it all.